Ninety% of ibuprofen is metabolised to inactive compounds while in the liver, largely by glucuronidation, to produce two metabolites - a hydroxylated compound along with a carboxylated compound. Obvious quantity of distribution is 0.fourteen L/kg. Ibuprofen and its metabolites commonly cross the placental barrier in Expecting animals (rabbits and rats). https://michaelh789vtq7.iamthewiki.com/user