At this time, There are 2 sorts of research on itaconate: Irg1−/− macrophages and the regulatory result of itaconate derivatives. Both of these benefits ended up complementary and uncovered which the regulatory mechanisms of itaconate involved alkylation on Keap1 to activate Nrf2, succinate dehydrogenase inhibition, activating transcription element three (ATF3) https://jaidenekpva.blogdomago.com/29038179/fascination-about-4-octyl-itaconate